Does Not Promote the Differentiation of A Spontaneously Arising Pancreatic Tumor
نویسندگان
چکیده
منابع مشابه
Genetically engineered murine pancreatic cancer models approximate immunophenotypic properties of human patients
Pancreatic ductal adenocarcinoma (PDA) has a prominent stroma which includes collagen, lymphoid, myeloid, and stellate cells. Adequate preclinical models are needed to advance immunotherapy for PDA. Indeed many xenograft models poorly mimic the morphology, stroma, and phenotype of the human PDA microenvironment. Thus, further development and use of relevant spontaneously arising genetically eng...
متن کاملBreast metastasis from the pancreatic neuroendocrine tumor origin detected by 99mTc-Octreotate scan
A 50 years old woman with history of pancreatic neuroendocrine tumor diagnosed 2 years ago, which has not been surgically removed,was referred to our department for a 99mTc-Octreotate in order to evaluate the somatostatin receptor status. She was treated with regular sandostatin injections and chemotherapy. Her CT scan which was previously performed confirmed lung, adrenal and hepati...
متن کاملتمایز بنیاختههای جنینی انسان به سلولهای مولد انسولین
Introduction: Type I diabetes mellitus is caused by autoimmune destruction of the insulin-producing β-cells. A new potential method for curing the disease is transplantation of differentiated insulin- secreting cells from human embryonic stem cells. Methods: Human embryonic stem cell lines (Royan H1) were used to produce embryoid bodies. Differentiation carried out by growth factor-mediated se...
متن کاملمروری بر سببشناسی و مارکرهای زیستی دخیل در تشخیص سرطان پانکراس با تاکید بر نقش دیابت در بروز این بیماری: مقاله مروری
Cancer is the major cause of death in the world and the rate of mortality is higher in developed countries. Therefore, lifestyle could be effective in promoting the cancer. The pancreatic tumors, are 8th cause of mortality due to cancer, which have several types, among them ductal adenocarcinoma is the most common and includes 85% of cases. Since, it is almost impossible to diagnosis the tumor ...
متن کاملWild Type p53 Gene Transfer Increases Chemosensitivity and Apoptotic Response of PANC-1 Pancreatic Tumor Cell Line
The effect of p53 gene therapy on chemosensitivity and apoptotic response of PANC-1 tumor cells, which express high amount of mutant p53, to cancer chemotherapeutic agents of Etoposide and Doxorubicin was investigated. Comparison of the chemosensitivity of PANC-1 cells to its wild type p53 transfectants showed that wt-p53 expressing transfectants are more sensitive to both Etoposide and Doxorub...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2004